For real change this year—begin within

For real change this year—begin within

Lose fat and reset your metabolism with nutrition designed for cellular renewal.

SHOP PROLON

For real change this year—begin within

Lose fat and reset your metabolism with nutrition designed for cellular renewal.

SHOP PROLON

1,000,000+ Happy Healthy Customers

Longevity nutrition for every day—and every goal

From deep cellular renewal and daily longevity nutrition to guided nutrition therapy, our products and programs are designed to help you feel your best today and thrive tomorrow.

5-Day Fasting Mimicking Diet

1M+ Happy Healthy Customers

5-Day Fasting Mimicking Diet

The patented program that gives you the benefits of fasting—while you eat.

Proven benefits no “detox” or drug can deliver

  • Fat loss with muscle protection
  • Cellular rejuvenation
  • Reverse biological aging with three consecutive cycles
SHOP 5-DAY
Next Gen Prolon 5-Day Fasting Mimicking Program

1M+ Happy Healthy Customers

Next Gen Prolon 5-Day Fasting Mimicking Program

The evolution of fasting science. Certified organic soups. Superior flavor. Ready-to-eat convenience.

Proven benefits no “detox” or drug can deliver

  • Lose fat while protecting muscle
  • Renew your cells
  • Reverse biological aging with three consecutive cycles
SHOP NEXT GEN

PROLON 5-DAY FASTING MIMICKING DIET

Reset your body, rejuvenate your cells—in five days

The most powerful changes come from within. That’s the science-backed principle at the heart of Prolon’s patented 5-day program. You get the benefits of fasting while eating nourishing food.

A cellular reset from within

A cellular reset from within

Cellular renewal

The only patented nutrition program that triggers your body’s natural cellular cleanup process and supports longevity.

Fat loss and muscle protection

Clinically proven to target visceral fat while protecting your precious lean muscle.

Metabolic health

Supports healthy metabolic markers. 20 days of the 5-Day FMD is as effective as 120 days of the Mediterranean Diet for heart health.

Longevity and biological age

Age on your terms. Three cycles of the 5-Day FMD reverses your biological age by 2.5 years.

Recommended by thousands of healthcare professionals

Dr. Beverly Yates
★★★★★

Dr. Beverly Yates

“Prolon is my first choice for patients looking for a simple and effective way to lose body fat while protecting their precious muscle mass, and to feel better overall. Cellular rejuvenation is the key to staying youthful and Prolon makes it easy.”

Dr. Joel Kahn, Cardiologist
★★★★★

Dr. Joel Kahn, Cardiologist

“I love the science supporting Prolon, and I love that the science has been published in multiple peer-reviewed journals. It allows me to recommend Prolon with confidence.”

Dr. Robert Lufkin
★★★★★

Dr. Robert Lufkin

“Prolon’s 5-Day Program helps you lose visceral fat, while you preserve lean muscle mass. It’s flexible, convenient, scientifically proven, safe, and it works.”

From the pioneers in longevity science

Prolon is the only nutrition program patented for supporting longevity, healthspan, and protecting lean body mass through cellular rejuvenation.

Years of scientific research

Years of scientific research

Decades of studies on longevity and nutrition

Clinical trials

Clinical trials

Conducted with world-leading institutions

Leading research institutions

Leading research institutions

Including USC, Stanford, Mayo Clinic, and more

Pending or issued patents

Pending or issued patents

For optimizing longevity and healthspan

A complete system for healthy aging

By mimicking fasting states, the clinically tested FMD initiates cellular rejuvenation, and targets visceral fat. It’s your periodic deep clean and systemic overhaul.

Prolon Life

Proven benefits

Grounded in decades of research, Prolon delivers real benefits that help you improve your health today and extend your healthspan tomorrow.

Weight loss

Weight loss

Weight loss is about more than the number on the scale. Unlike extreme diets and drugs, Prolon helps you lose the weight you want to lose—visceral fat—while protecting your lean muscle.

Healthy aging

Healthy aging

Prolon is the only nutrition program patented for supporting longevity through cellular renewal. Research shows that three consecutive monthly cycles of the Prolon FMD can reduce your biological age by 2.5 years.

Skin

Skin

The Prolon 5-Day FMD can increase skin hydration and give you a more radiant complexion. It’s skincare from the inside out.

Cellular renewal

Cellular renewal

The Prolon FMD is the only nutrition program clinically proven to kickstart autophagy, your body’s natural cellular rejuvenation process.

Mental clarity

Mental clarity

Prolon activates ketosis, a fat-burning state known for brain-boosting benefits—many users report better focus and mental clarity post-fast.

Metabolic health

Metabolic health

20 days of Prolon is as effective as 120 days of the Mediterranean diet on heart health, and supports healthy cardiometabolic markers.

1,000,000+ Happy Healthy Customers

Backed by science, loved by users

- Zaree
★★★★★

- Zaree

“It works—weight management, energy, and mental clarity.”

- Amy
★★★★★

- Amy

“I lost 5 pounds my first round and felt amazing.”

- Tracy
★★★★★

- Tracy

“Love it and recommend over GLP-1 shots.”

Our difference

Our difference

Natural solutions, whole-health benefits: Our products and programs work with your body, tapping into its innate ability to heal.

Biotech-level scientific rigor: 25+ years of peer-reviewed research, 40+ clinical trials, 18 top-tier university research partners.

Expert support: We offer 1-on-1 coaching and structured programs.

Trusted worldwide: 1 million users, recommended by thousands of healthcare professionals.

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FAQs

How do I use the Prolon FMD?

Follow the day-by-day meal plan included with your program.

How does the FMD renew my cells?

The program is designed around fasting-responsive cellular pathways.

What happens during the FMD cycle?

Your body transitions through five days of carefully designed nutrition.

Will I lose weight on the program?

Individual results vary. Consult your healthcare professional.

What are the food pathways affected by Prolon?

Prolon is designed to support metabolic and cellular pathways associated with fasting.

What is the daily caloric intake during Prolon?

Daily intake varies by program day; follow the included guide.

What’s different about the Prolon Next Gen 5-Day program?

Next Gen adds organic, ready-to-eat, flavor-packed soups.